Washing hands makes dry or cracked skin worse ... unless you use Gloves in a Bottle!. Gloves in a Bottle is grease-less, fragrance-free, hypoallergenic and completely nontoxic, and does not wash off. Gloves in a Bottle is the most effective skin protectant of its kind for dry, red or irritated skin. Gloves in a Bottle is used daily by a wide range of health care professionals. How does Gloves in a Bottle work The soothing lotion rapidly absorbs into the outer layer of skin to form a barrier that helps prevent water and irritants (cleaners, detergents, paint and thinners, cement, solvents, gasoline, gardening chemicals, etc.) from penetrating the skin. The skin is still able to breathe and retain natural moisture and oils. Gloves in a Bottle is undetectable once absorbed, and comes off naturally as your skin exfoliates. Reapply every four hours for continued protection.