Doctor recommended for adults. Immediate cooling soothing relief. Also for headache fever. Lasts up to 8 hours. Ready to use. Safe to use with medication. Each sheet: 2 inch x 5-1/8 inch. Doctor recommended to provide cooling relief from the discomfort associated with migraine, headache, fever, muscle aches, sprains, over - exertion, hot flashes or whenever you need relief. Provides immediate cooling relief in a convenient disposable product. Needs no refrigeration and is portable. Ready to use anywhere ad anytime at home, at work or while traveling. Gently adheres to your skin. Offers just the right amount of cooling to maximize comfort. Cooling effect of each sheet lasts up to 8 hours. Since Be Koool gel sheets are non- medicated, they are safe to use with medications. Made in China.